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EPIGENETIC REGULATION AND CANCER DEVELOPMENT

Dr Zdenko Herceg received 5 different grants from Fondation ARC on the last decade. His Group conducts both mechanistic studies and epigenetic profiling, aiming to gain a better mechanistic understanding of tumorigenesis, and to discover and validate new cancer biomarkers.

Zdenko Herceg is the Head of the Group “Epigenetics” and since 2011, of the Section “Mechanisms of Carcinogenesis” at the International Agency for Research on Cancer (IARC, also known as CIRC in French) located in Lyon. He joined IARC in 1997 after a Ph.D. from the University of St Andrews (UK) in the field of oncogenic transformation of human epithelial cells, and a post-doctorate in the Research Institute of Molecular Pathology (IMP) in Vienna, Austria.

His laboratory conducts both mechanistic studies and epigenetic profiling, aiming to gain a better mechanistic understanding of tumorigenesis, and to discover and validate new cancer biomarkers. His research exploits new concepts in cancer epigenetics and recent technological advances in genomics and is carried out in close collaboration with national and international groups.*

Zdenko Herceg's research has been supported in part by funding from la Fondation ARC through five different grants. As he explains: "when I got the first funding I was a young scientist developing my own group and a new activity. Later on, these contributions helped me to set up successful collaborations, to build up a research team and my own scientific career as the head of a group and later as head of research section". In this exclusive interview, Zdenko Herceg comments on his work on the role of epigenetics in cancer development.

*For more information of Zdenko Herceg’s work :http://www.iarc.fr/en/research-groups/EGE/staff.php


Entretien réalisé par A.G.

Crédits photos: Fondation ARC